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PFDN5 Antibody, Biotin conjugated

Datasheet
Code CSB-PA01414D0Rb
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PFDN5 Polyclonal antibody
Uniprot No.
Q99471
Target Names
PFDN5
Alternative Names
1190001O17Rik antibody; 1700010A06Rik antibody; c myc binding protein antibody; c-myc binding protein MM 1 antibody; C-myc-binding protein Mm-1 antibody; D15Ertd697e antibody; EIG 1 antibody; Eig1 antibody; MGC5329 antibody; MGC71907 antibody; MM 1 antibody; MM1 antibody; Myc modulator 1 antibody; PFD5 antibody; PFD5_HUMAN antibody; PFDN5 antibody; Prefoldin 5 antibody; Prefoldin subunit 5 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Prefoldin subunit 5 protein (2-154AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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PFDN5 Proteins

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Target Background

Function
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC.
Gene References into Functions
  1. Results from a study on gene expression variability markers in early-stage human embryos shows that PFDN5 is a putative expression variability marker for the 3-day, 8-cell embryo stage. PMID: 26288249
  2. interaction with p73 PMID: 11844794
  3. MM-1alpha, MM-1gamma, and MM-1gamma, but not MM-1beta, were found to repress transcription activity of c-Myc PMID: 16173081
  4. Wnt4 gene, a member of the Wnt-beta-catenin pathway, was identified as a target gene of MM-1. PMID: 18281035
Subcellular Location
[Isoform 1]: Nucleus.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Nucleus.
Protein Families
Prefoldin subunit alpha family
Tissue Specificity
Highly expressed in pancreas and skeletal muscle and moderately in other tissues.
Database Links

HGNC: 8869

OMIM: 604899

KEGG: hsa:5204

STRING: 9606.ENSP00000334188

UniGene: Hs.655327

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